【臨床症状】70代 膵臓癌 肺気腫
【問題】画像所見と診断名は?
CT_20240817125428_Image005
CT_20240817125428_Image006
CT_20240817125428_Image007
CT_20240817125428_Image008
CT_20240817125428_Image009
CT_20240817125428_Image010
CT_20240817125428_Image011
CT_20240817125428_Image012
CT_20240817125428_Image013
CT_20240817125428_Image014
CT_20240817125428_Image015
CT_20240817125428_Image016
CT_20240817125428_Image017
CT_20240817125428_Image018
CT_20240817125428_Image019
CT_20240817125428_Image020
CT_20240817125428_Image021
CT_20240817125428_Image022
CT_20240817125428_Image023
CT_20240817125428_Image024
CT_20240817125428_Image025
CT_20240817125428_Image026
CT_20240817125428_Image027
CT_20240817125428_Image028
CT_20240817125428_Image029
CT_20240817125428_Image030
CT_20240817125428_Image031
CT_20240817125428_Image032
CT_20240817125428_Image033
CT_20240817125428_Image034
CT_20240817125428_Image035
CT_20240817125428_Image036
CT_20240817125428_Image037
CT_20240817125428_Image038
CT_20240817125428_Image039
CT_20240817125428_Image040
CT_20240817125428_Image041
CT_20240817125428_Image042
CT_20240817125428_Image043
CT_20240817125428_Image044
CT_20240817125428_Image045
CT_20240817125428_Image046
CT_20240817125428_Image047
CT_20240817125428_Image048
CT_20240817125428_Image049
CT_20240817125428_Image050
CT_20240817125428_Image051
CT_20240817125428_Image052
CT_20240817125428_Image053
CT_20240817125428_Image054
CT_20240817125428_Image055
CT_20240817125428_Image056
CT_20240817125428_Image057
CT_20240817125428_Image058
CT_20240817125428_Image059
CT_20240817125428_Image060
CT_20240817125428_Image061
CT_20240817125428_Image062
CT_20240817125428_Image063
CT_20240817125428_Image064
CT_20240817125428_Image075
CT_20240817125428_Image076
CT_20240817125428_Image077
CT_20240817125428_Image078
CT_20240817125428_Image079
CT_20240817125428_Image080
CT_20240817125428_Image081
CT_20240817125428_Image082
CT_20240817125428_Image083
CT_20240817125428_Image084
CT_20240817125428_Image085
CT_20240817125428_Image086
CT_20240817125428_Image087
CT_20240817125428_Image088
CT_20240817125428_Image089
CT_20240817125428_Image090
CT_20240817125428_Image091
CT_20240817125428_Image092
CT_20240817125428_Image093
CT_20240817125428_Image094
CT_20240817125428_Image095
CT_20240817125428_Image096
CT_20240817125428_Image097
CT_20240817125428_Image098
CT_20240817125428_Image099
CT_20240817125428_Image100
CT_20240817125428_Image101
CT_20240817125428_Image102
CT_20240817125428_Image103
CT_20240817125428_Image104
CT_20240817125428_Image105
CT_20240817125428_Image106
CT_20240817125428_Image107
CT_20240817125428_Image108
CT_20240817125428_Image109
CT_20240817125428_Image110
CT_20240817125428_Image111
CT_20240817125428_Image112
CT_20240817125428_Image113
CT_20240817125428_Image114
CT_20240817125428_Image115
CT_20240817125428_Image116
CT_20240817125428_Image117
CT_20240817125428_Image118
CT_20240817125428_Image119
CT_20240817125428_Image120
CT_20240817125428_Image121
CT_20240817125428_Image122
CT_20240817125428_Image123
CT_20240817125428_Image124
CT_20240817125428_Image125
CT_20240817125428_Image126
CT_20240817125428_Image127
CT_20240817125428_Image128
CT_20240817125428_Image129
CT_20240817125428_Image130
CT_20240817125428_Image131
CT_20240817125428_Image132
CT_20240817125428_Image133
CT_20240817125428_Image134
CT_20240817125428_Image143
CT_20240817125428_Image144
CT_20240817125428_Image145
CT_20240817125428_Image146
CT_20240817125428_Image147
CT_20240817125428_Image148
CT_20240817125428_Image149
CT_20240817125428_Image150
CT_20240817125428_Image151
CT_20240817125428_Image152
CT_20240817125428_Image153
CT_20240817125428_Image154
CT_20240817125428_Image155
CT_20240817125428_Image156
CT_20240817125428_Image157
CT_20240817125428_Image158
CT_20240817125428_Image159
CT_20240817125428_Image160
CT_20240817125428_Image161
CT_20240817125428_Image162
CT_20240817125428_Image163
CT_20240817125428_Image164
CT_20240817125428_Image165
CT_20240817125428_Image166
CT_20240817125428_Image167
CT_20240817125428_Image168
CT_20240817125428_Image169
CT_20240817125428_Image170
CT_20240817125428_Image171
CT_20240817125428_Image172
CT_20240817125428_Image173
CT_20240817125428_Image174
CT_20240817125428_Image175
CT_20240817125428_Image176
CT_20240817125428_Image177
CT_20240817125428_Image178
CT_20240817125428_Image179
CT_20240817125428_Image180
CT_20240817125428_Image181
CT_20240817125428_Image182
CT_20240817125428_Image183
CT_20240817125428_Image184
CT_20240817125428_Image185
CT_20240817125428_Image186
CT_20240817125428_Image187
CT_20240817125428_Image188
CT_20240817125428_Image189
CT_20240817125428_Image190
CT_20240817125428_Image191
CT_20240817125428_Image192
▶答えはこちら
- 右肺に胸膜肥厚と石灰化を認める
- また右肺に小さな結節影が散見されるも、肉芽腫病変疑い
- 気腫性変化を認めるも、縦隔リンパ節腫大や胸水は認めない
- また膵尾部に既知の膵癌、また腹水の貯留も認める
- 上記より、陳旧性結核性胸膜炎疑いと診断された
【結核性胸膜炎】
・結核性胸膜炎は癌性胸膜炎と並び、胸水貯留を認める代表的な疾患
・結核性胸膜炎は、胸水貯留を認めかつ、喀痰や胸水穿刺、胸膜生検などで結核菌が検出されたもの、もしくは胸膜生検で病理組織学的に乾酪性肉芽腫が証明されたものと定義されている
・ただし胸水や胸膜から結核菌が検出される割合は少ない
・そのため、結核菌が検出されなくてもadenosine deaminase:ADA 高値で単核球優位の滲出性胸水であれば診療的に診断される事もある
臨床的に診断され、治療を開始することも多い
・主な症状は咳嗽、胸痛、発熱、呼吸困難など
・画像所見は、片側のみの(大量)胸水を認め、胸膜肥厚や浸潤影を認める
・陳旧性の場合は胸膜の石灰化を認める事もある
参考書籍:困ったときの胸部の画像診断
参考文献:小澤貴裕, 三藤久, 小栗明人 他, 結核性胸膜炎の確定診断および薬剤感受性試験における局所麻酔下胸腔鏡検査の有効性, 北里大学2022.52:1-5
青江啓介, 平木章夫, 村上知之, 結核性胸膜炎の診断と治療, 結核第79巻 第4号